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Icf i growth factor breast cancer

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Metrics details. Both autocrine and paracrine signaling may be involved in conferring this selective advantage. For example, oncogenic activation of the Ras pathway, acting via MAP kinases, causes phosphorylation of Smad2 and Smad3 at specific Erk consensus sites in the linker region between their DNA binding and transcriptional activation domains. DE and Smad2. Some evidence suggests that the latter may follow alternative signaling pathways, perhaps in cooperation with activated oncogenes.
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The role of the insulin-like growth factor-1 system in breast cancer

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The role of the insulin-like growth factor-1 system in breast cancer | Molecular Cancer | Full Text

The purpose of this study was to explore the risk factors for breast cancer and establish the expression rate of IGF-2 in female patients. A case control study with people in case group and people in control group. A self-administered questionnaire was used to investigate risk factors for breast cancer. All cases were interviewed during a household survey.
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Role of Insulin-Like Growth Factor 1 in HER2-Positive Breast Cancer Patients

By William J. Cromie Gazette Staff. Date April 22, September 20,
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Metrics details. Mammographic density MD is a strong breast cancer risk factor that reflects fibroglandular and adipose tissue composition, but its biologic underpinnings are poorly understood. Insulin-like growth factor binding proteins IGFBPs are markers that may be associated with MD given their hypothesized role in breast carcinogenesis.
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